David Robbe, PhD                                   

 

Born                            Pontarlier, France on 10th June 1976

Nationality                   French

Marital status              Married

 

Contact Information

 

[Laboratory]                 Center for Molecular and Behavioral Neuroscience

Rutgers University        

197 University Avenue                                                                  

Newark, New Jersey 07102

USA

Tel. 973-353-1080 ext3360

Fax. 973-353-1820

                                   

 

[Home]                         419, 7th Street

Harrison

New-Jersey 07029

USA

                                    Tel. 973-482-2952

 

robbe@andromeda.rutgers.edu

 

http://osiris.rutgers.edu/~david/

 

 

 

Current Position

 

Research Assistant Professor. Center for Molecular and Behavior Neuroscience, Rutgers, Newark, NJ, USA

Directed by Gyorgy Buzsaki, MD, PhD.  Fellowship from the Human Frontier Science Organization

Techniques mastered:  Tetrodes and silicone probes recording on head-restrained and freely moving rats. Patch-clamp recording in slice. Pharmacology. Behavior and programing of behavioral set-up (LabView). Analysis of spike train and local field potential (Matlab)

 

 

Education/Research Background

 

                       

2003-2005         Post-doctoral Associate. Center for Molecular and Behavior Neuroscience, Rutgers, Newark, NJ, USA.

Techniques :  Tetrodes and silicone probes recording on head-restrained and freely moving rats. Pharmacology. Behavior, Analysis.

Directed by Gyorgy Buzsaki, MD, PhD. Granted by Human Frontier Science Organization and EMBO (first year)

 

1999-2002      Graduate student and PhD candidate. Subject: Synaptic Plasticity and Addiction. Specialty: Electrophysiology and pharmacology. Thesis Advisor: Dr. J. Bockaert. Under the scientific responsibility of Dr O. Manzoni. PhD obtained the 22nd of October 2002. Thesis grant from the French Ministry of Research and Technology

 

1998-1999         Diplomee dEtudes Approfondies (Post graduate professional diploma), "Neurobiology, Grade B, First.

                        University of Montpellier II

 

1997-1998         Maitrise (Master of Science ) de Biologie Cellulaire et Physiologie

                        University of Paris VI. Ecole Normale Superieure d'ULM Paris

 

1996-1997         Licence (Bachelor of Science) de Biologie Cellulaire et Physiologie

                        University of Paris VI. Ecole Normale Superieure d'ULM Paris

  

 

 

 

Professional Experiences

 

2001-2002         Teaching experiences at the University of Montpellier II

 

09/98-06/99       Centre National de Recherches Scientifiques UPR 9023

 

Training course: Molecular biology and pharmacology laboratory (Dr. L. Fagni). Subject: Regulation of mGlu5 membrane trafficking by Homer protein . Specialties : patch-clamp, immunofluorescence, neuronal transfection, primary cultures of cerebellum

 

07/97-08/98       Institut National de la Sante et de la Recherche Medicale U259

Training course: (Dr N. Abrous). Subject: Neurogenesis and PSA-NCAM in the adult rat hippocampus. Immunohistochemistry

 

 

 

Publications

 

Robbe,D., Montgomery,S.M., Thome,A.,Rueda-Orozsco,P.E., McNaughton,B.L., and Buzsaki,G.
Cannabinoids reveal importance of spike timing coordination in hippocampal function
Nature Neuroscience (2006), 9, 1526-33.

Mato,S., Robbe,D., Puente,N., Grandes,P., and Manzoni,O.J.
Presynaptic homeostatic plasticity rescues long-term depression after chronic Delta9-tetrahydrocannabinol exposure.
J. Neurosci. (2005), 25, 11619-11627.

Mato,S., Chevaleyre,V., Robbe,D., Pazos,A., Castillo,P.E., and Manzoni,O.J.
A single in-vivo exposure to delta 9THC blocks endocannabinoid-mediated synaptic plasticity.
Nat. Neurosci. (2004), 7, 585-586.

Robbe,D., Alonso,G., and Manzoni,O.J.
Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens.
Ann. N. Y. Acad. Sci. (2003), 1003, 212-225.

Ango,F., Robbe,D., Tu,J.C., Xiao,B., Worley,P.F., Pin,J.P., Bockaert,J., and Fagni,L.
Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons.
Mol. Cell Neurosci. (2002), 20, 323-329.

Robbe,D., Alonso,G., Chaumont,S., Bockaert,J., and Manzoni,O.J.
Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses.
J. Neurosci. (2002), 22, 4346-4356.

Robbe,D., Kopf,M., Remaury,A., Bockaert,J., and Manzoni,O.J.
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens.
Proc. Natl. Acad. Sci. U. S. A (2002), 99, 8384-8388.

Robbe,D., Bockaert,J., and Manzoni,O.J.
Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice.
Eur. J. Neurosci. (2002), 16, 2231-2235.

Robbe,D., Alonso,G., Duchamp,F., Bockaert,J., and Manzoni,O.J.
Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.
J. Neurosci. (2001), 21, 109-116.

Ango,F., bani-Torregrossa,S., Joly,C., Robbe,D., Michel,J.M., Pin,J.P., Bockaert,J., and Fagni,L.
A simple method to transfer plasmid DNA into neuronal primary cultures: functional expression of the mGlu5 receptor in cerebellar granule cells.
Neuropharmacology (1999), 38, 793-803. 

 

 

 

Awards/Grants Received

 

                        EMBO long term fellowship in 2003

                        Human Frontier Long Term Fellowship 2004

 

 

 

 

 

 

Meetings

 

            Robbe, D., Montgomery, S., and Buzsaki, G. (2005). Cannabinoids destroy cell assembly coordination in the hippocampus. SFN 35th Annual Meeting. Washington, DC, USA. November 12-16.

            Robbe, D., Montgomery, S., and Buzsaki, G. (2005). Cannabinoid receptor activation disrupts cell assembly coordination in the hippocampus. Gordon Conferences : Cannabinoid Function in the CNS. Bates College, ME, USA. July 17-22.

            Robbe, D. and Buzsaki, G. (2004). Cannabinoids and endocannabinoids on the hippocampal network of behaving rats. Human Frontier Annual Meeting. Hakone, Japan. May 14-18.

            Robbe, D. and Buzsaki, G. (2004). Cannabinoids and endocannabinoids on the hippocampal network of behaving rats. Computational and System Neuroscience Meeting. Cold Spring Harbor Laboratory, NY, USA. March 24-28.

            Robbe, D., Kopf, M., Remaury, A., Bockaert, J., and Manzoni, O. J. (2002). Endogenous cannabinoids mediate long-term synaptic plasticity in the nucleus accumbens. 3rd Forum of European Neuroscience. Paris, France. July 13-17.

            Robbe, D., Bockaert, J., and Manzoni, O. J. (2002). Endogenous cannabinoids mediate long-term synaptic plasticity in the nucleus accumbens. Winter Conference on Neurochemistry. S�den, Austria. April 6-11.

            Robbe, D., Bockaert, J., and Manzoni, O. J. (2001). L'activation des r�epteurs metabotropiques du glutamate du groupe II induit une d�ression �long terme �la synapse glutamatergique du noyau accumbens de souris. 5 Colloque de la Socit�des Neurosciences (french). Toulouse, France. May 28-31.

Robbe, D., Bockaert, J., and Manzoni, O. J. (2001). Control of synaptic plasticity by mGluR2/3 at the mouse nucleus accumbens synapses. SFN 31st Annual Meeting. San Diego, CA, USA. November 10-15.